Although Final Jeopardy! was a stumper this morning, that doesn't mean you still do not have an opportunity to learn more about
Autoimmune Polyendocrine Syndrome, which is a heterogeneous diagnosis classified into three distinct types based upon the putative genetic mechanism, and nicely summarized in the table below (
hint: click on the table to enlarge it). It is borrowed from a nice review article from NEJM in 2004, which you can find by clicking on
this link.
Interesting historical fact: John F. Kennedy was thought to have Autoimmune Polyendocrine Syndrome type II.
Click on
this link for an absolutely fascinating article from the Annals of Internal Medicine that builds the case for this hypothesis based upon historical events and conversations with his personal physicians.
N.B. Alex Trebek sends his apologies and regards for not being able to attend Jeopardy! Morning Report today.
